李多川（Li Duochuan, Li DC）

      Li Duochuan received a PhD in 1996 from China Agricultural University. He is currently professor in Shandong Agricultural University. He has undertaken about 10 projects, such as NSFC, 863 program and National Key Technology Research and Development program. He has published more than 50 peer-reviewed papers in international journals and has been granted 4 patents.

Research Focus

1.  Thermophilic Fungi: Diversity, structure and function of thermostable enzymes, and adaptation to high temperature.

2.  Pathogenic Fungi: Pathogen association molecular pattern (PAMP)from Rhizoctonia solani.

3. Acidophilic Fungi: Diversity and adaptation to acid environment.

Selected Publications

1.  Chen JY, Guo XN, Zhu M, Chen C, Li DC. 2019. Polysaccharide monooxygenase catalyzation of the oxidation of cellulose to form glucuronic acid-containing cello-oligosaccharides. Biotechnol Biofuels12:42.

2. Mohsin I, Poudel N, Li DC, Papageorgiou AC. 2019. Crystal structure of a GH3 β-glucosidase from the thermophilic fungus Chaetomium thermophilum.Int J Mol Sci 20: 5962.

3. Chen C, Chen JY, Geng ZG, Wang MX, Liu N, Li DC. 2018. Regioselectivity of oxidation by a polysaccharide monooxygenase from Chaetomium thermophilum. Biotechnol Biofuels 11:155.

4. Papageorgiou AC, Chen J, Li DC. 2017. Crystal structure and biological implications of a glycoside hydrolase family 55 β-1,3-glucanase from Chaetomium thermophilum. Biochimica et Biophysica Acta-Proteins and Proteomics,1865:1030-1038.

5. Ma YN, Han C, Chen JY, Li HY, He K, Liu AX, Li DC.2015. Fungal cellulase is an elicitor but its enzymatic activity is not required for its elicitor activity. Molecular Plant Pathology 16:14-26.

6. Papageorgiou AC, Li DC. 2015. Expression, purification and crystallization of a family 55 beta-1,3-glucanase from Chaetomium thermophilum. Acta Cryst F 71:680-683.

7. Xu XX, Chen JY, Xu HJ, Li DC. 2014. Role of a major facilitator superfamily transporter in adaptation capacity of Penicillium funiculosum under extreme acidic stress. Fungal Genet Biol 69: 75-83.

8. Teemu H, Frioux C, Zhnag LQ, Li DC, Papageorgiou AC. 2014. Crystal structure and biochemical characterization of a manganese superoxide dismutase from Chaetomium thermophilum. Biochimica et Biophysica Acta-Proteins and Proteomics 1844:422-429.

9. Wang F, Li AN, Dai DM, Xu XX, Li DC. 2013. A new halotolerant species of Alternaria from Qinghai-Tibet Plateau, China. Mycotaxon 123:251-253.

10. Wang XJ, Peng YJ, Zhang LQ, Li AN, Li DC. 2012. Directed evolution and structural prediction of cellobiohydrolase II from the thermophilic fungus Chaetomium thermophilum. Appl Microbiol Biotechnol 95:1469–1478.

11. Li AN, Yu K, Liu HQ, Zhang J, Li H, LiDC. 2010.Two novel thermostable chitinase genes from thermophilic fungi: cloning, expression and characterization. Bioresourse Technol 101:5546-5551.

12. Wakadkar S, Zhang LQ, Li DC, Haikarainen T, Dhavala P, Papageorgiou AC. 2010. Expression, purification and crystallization of Chaetomium thermophilum Cu/Zn superoxide dismutase. Acta Crystallogr Sect F Struct Biol Cryst Commun 66:1089-1092.

Patents

1.  Li DC，Yang ZQ. 2020. A mutant of exoglucanase from Myceliophthora thermophila and its application. China Patent, No. ZL201711226279.2.

2. Li DC, LI AN, Han S. 2015. Yeast engineering strain expressing a mutant of lipase from Thermomyces lanuginusus. China Patent, No. ZL201310204916.4.

3. Li DC, Han C. 2015. Yeast engineering strain expressing AA9 CtAA9d from Chaetomium thermophilum. China Patent, No. ZL201310422852.5.

4. Li DC, C J. 2009. Yeast engineering strain expressing GLA from Chaetomium thermophilum and its construction method. China Patent, No. ZL200610043937.2.

Books

1.  Li DC, Papageorgiou AC. 2019.Cellulases from Thermophilic Fungi: Recent Insights and Biotechnological Potential. In: Fungi in Extreme Environments: Ecological Role and Biotechnological Significance (Edited by Sonia TA, Martin G), Springer Publishers.

2. Li DC. 2015. Cellulases from Thermophilic Fungi. In:Thermophilic Microorganisms (Edited byFL Li). Caister Academic Press.

3. Li DC, Li AN. 2009. Current Advances in Fungal Chitinases. In:Applied Mycology (Edited by Rai M, Bridge PD). CABI.

E-mail: lidc20@sdau.edu.cn, Tel: 0538-8249071